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Stanford study ID & Name & Description & Vaccines & Data in FluPRINT\\
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SLVP015 & Comparison of immune responses to influenza vaccine in adults of different ages (2007-2017) & Who: 18-100yo healthy participants How: immunized annually with the seasonal inactivated influenza vaccines from 2007-2017 When: Blood samples acquired before immunization (Day 0), on days 6-8 and 28 after immunization & 2007-2013 Seasonal trivalent, inactivated influenza vaccines (Fluzone) 2014-2015 High Dose trivalent Fluzone for participants $geq$ 65yo and quadrivalent Fluzone for younger participants & 135 donors Assays: 51-plex Luminex 62-plex Luminex MSD 4plex MSD9plex Other Luminex HAI CMV/EBV Hormones CyTOF phenotype Lyoplate Phospho Cytof pheno Phospho cytof phospho Phosphoflow CBCD\\
SLVP017 & B-cell immunity to influenza (2009-2011 and 2013) & Who: 1-2yo (2013), 8-100yo healthy participants who did not receive the seasonal influenza vaccine in previous years (2010, 2011 and 2013) How: immunized with either seasonal inactivated or live, attenuated influenza vaccines in 2009, 2010, 2011 and 2013 When: Blood samples acquired before immunization (Day 0) and on day 28 after immunization & 2009-2011 Seasonal trivalent, inactivated influenza vaccines (Fluzone) or seasonal live, attenuated influenza vaccine (FluMist) 2013 Seasonal trivalent inactivated influenza vaccine- (Fluzone) - pediatric formulation for 1-2yo children & 153 donors Assays: 51-plex Luminex 62-plex Luminex HAI CMV/EBV CyTOF phenotype CBCD\\
SLVP018 & T-cell and general immune response to seasonal influenza vaccine (2009-2013) & Who: 1-8yo (2013), 8-100yo healthy participants How: immunized with either seasonal inactivated or live, attenuated influenza vaccines from 2009-2013 When: Blood samples acquired before immunization (Day 0), days 7-10 and 28 after immunization & 2009-2010 Seasonal trivalent inactivated influenza vaccine (Fluzone) or seasonal trivalent live attenuated influenza vaccine (FluMist) 2010 High Dose trivalent Fluzone for participants $geq$ 65yo 2013 Seasonal trivalent, inactivated influenza Pediatric Dose (Fluzone, 0.25 ml) for 1-3yo children & 249 donors Assays: 51-plex Luminex 62-plex Luminex MSD 4plex MSD 9plex HAI CMV/EBV Hormones CyTOF phenotype Lyoplate Phospho Cytof pheno Phospho cytof phospho Phosphoflow CBCD\\
SLVP021 & Plasmablast trafficking and antibody response in influenza vaccination (2011-2014) & Who: 8-34yo healthy participants who did not receive the seasonal influenza vaccine in previous years How: immunized with either seasonal inactivated influenza vaccines, given intramuscularly or intradermally, or live, attenuated influenza vaccines from 2011-2014 When: Blood samples acquired before immunization (Day 0), days 6-8 and 24-32 after immunization & 2011-2014 Seasonal trivalent inactivated influenza vaccine (Fluzone) given either intramuscularly or intradermally 2011-2012 Seasonal trivalent live attenuated influenza vaccine (FluMist) & 84 donors Assays: 51-plex Luminex 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype Phospho Cytof pheno Phospho cytof phospho Phosphoflow CBCD\\
SLVP024 & Protective mechanisms against a pandemic respiratory virus (2012) & Who: 2-9yo healthy participants How: immunized with the seasonal live, attenuated influenza vaccine When: Blood samples only from 18-2yo adults acquired before immunization (Day 0), days 7 and 28 after immunization & Seasonal live, attenuated influenza vaccine (FluMist) & Donors: 8 Assays: HAI Phosphoflow\\
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SLVP028 & Genetic and environmental factors in the response to influenza vaccination (2014-2018) & Who: 12-9yo healthy participants How: immunized with either seasonal inactivated or live, attenuated influenza vaccines from 2014-2018 When: Blood samples acquired before immunization (Day 0), days 6-8 and 28 + 7 after immunization & Seasonal quadrivalent inactivated influenza vaccine (Fluzone) or seasonal quadrivalent live attenuated influenza vaccine (FluMist) & Donors: 52 Assays: 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype\\
SLVP029 & Innate and acquired immunity to influenza infection and immunization (2014-2017) & Who: 6 mo-49yo healthy participants (who did not receive LAIV in the prior season nor received influenza immunizations in two or more prior seasons) How: immunized with either seasonal inactivated or live, attenuated influenza vaccines from 2014-2017 When: Blood samples acquired before immunization (Day 0), days 7 and 28 after immunization. Children <9 yrs received 2 immunizations with the second blood samples acquired 28 days after second immunization & Seasonal quadrivalent inactivated influenza vaccine (Fluzone) or seasonal quadrivalent live attenuated influenza vaccine (FluMist) & Donors: 47 Assays: 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype\\
SLVP030 & The role of CD4+ memory phenotype, memory, and effector t cells in vaccination and infection (2014-2019) & Who: 6 mo-10yo healthy participants How: immunized annually with either seasonal inactivated or live, attenuated influenza vaccines from 2014-2019 When: Blood samples acquired before immunization (Day 0), days 7 and 60 after immunization. Children with no prior influenza vaccine received 2 immunizations with the second blood sample acquired 60 days after second immunization & Seasonal quadrivalent inactivated influenza vaccine (Fluzone) or seasonal quadrivalent live attenuated influenza vaccine (FluMist) Seasonal trivalent, inactivated influenza Pediatric Dose (Fluzone, 0.25 ml) for 6-35mo children & Donors: 12 Assays: 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype\\
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