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authorMike Vink <mike1994vink@gmail.com>2021-04-23 17:30:09 +0200
committerMike Vink <mike1994vink@gmail.com>2021-04-23 17:30:09 +0200
commit19c3d0dba64d782e519d8ece36028ebb25b33141 (patch)
tree4534be50f304a6de41cd58ac29e32c437ecf3c9c /data_understanding
parentb64b582e8cbb54e851f00be06ab44fd7811286f1 (diff)
demo table and fig
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@@ -139,10 +139,22 @@ mining modelling process to replicate these results.
In the work of \cite{tomicFluPRINTDatasetMultidimensional2019} data on
indiviuals enrolled in influenza vaccine studies at the Stanford-LPCH Vaccine
-Program was collected, this data was archived at the Stanford Data Miner. This
+Program was collected, the data was archived at the Stanford Data Miner. This
archive was filtered by assays used in influenza studies, resulting in data
from 740 healthy donors, enrolled in influenza vaccine studies conducted by the
-Stanford-LPCH Vaccine Program from 2007 to 2015.
+Stanford-LPCH Vaccine Program from 2007 to 2015. These studies are described in
+the table accompanying the online publication of the fluprint dataset
+\autoref{tbl:studiesDesc}. From those 740 donors a vaccine response
+classification was only given for 372 donors \autoref{fig:demoResponder}, by a
+method that will be described in the section describing the data table
+containing this attribute. Overall there was no major difference in demographic
+statistics when stratisfying the data in high or low responders
+\autoref{fig:demoResponder}.
+
+Importantly in all studies the donors are only vaccinated once, except in the
+study SLVP015, participants here were vaccinated annually from 2007-2015
+\autoref{tbl:studiesDesc}. In all other studies participants would only be
+studied within the scope of one influenza season.
\fptable{studies_table}{.7}
{Reference table of clinical studies}
@@ -152,7 +164,42 @@ rest of the columns.}
{tbl:studiesDesc}
-i'm some text \autoref{tbl:studiesDesc}
+\begin{figure}
+ \includegraphics[width=\textwidth]{demographic}
+ \label{fig:demoResponder}
+ \caption{\textbf{A.} percentage of donors with factor property within high
+ and low responder groups. Included are sex, race, and CMV status
+ information. \textbf{B.} Age distribution of donors with a known response
+ classification.}
+\end{figure}
+
+\begin{table}
+\centering
+\begin{tabular}{ll}
+\toprule
+\textbf{Age (y)} & \\
+\midrule
+Mean $\pm$ SD & 21.02 $\pm$ 8.66\\
+Median (min. to max. range) & 22.5 ( 1 - 50 )\\
+\addlinespace
+ \textbf{Gender} & \\
+\midrule
+Male (\%) & 154 ( 41.4 )\\
+Female & 218 ( 58.6 )\\
+\addlinespace
+ \textbf{Ethnicity} & \\
+\midrule
+Caucasian (\%) & 187 ( 50.3 )\\
+African American (Black) (\%) & 4 ( 1.1 )\\
+Asian (\%) & 53 ( 14.2 )\\
+Hispanic/Latino (\%) & 5 ( 1.3 )\\
+Other (\%) & 121 ( 32.5 )\\
+Unknown (\%) & 2 ( 0.5 )\\
+\bottomrule{}
+\end{tabular}
+ \caption{\textbf{Demographic statistics of donors with known vaccine response classification.}}
+\end{table}
+
\citep{chattopadhyaySinglecellTechnologiesMonitoring2014}
The complex heterogeneity of cells, and their interconnectedness with each