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authorMike Vink <mike1994vink@gmail.com>2021-04-23 09:51:56 +0200
committerMike Vink <mike1994vink@gmail.com>2021-04-23 09:51:56 +0200
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+,Stanford study ID,ClinicalTrials.gov ID,Name,Description,Vaccines,Data in FluPRINT,ImmPort ID (www.immport.org),Ref.
+0,SLVP015,NCT01827462,Comparison of immune responses to influenza vaccine in adults of different ages (2007–2017),"Who: 18–100yo healthy participants How: immunized annually with the seasonal inactivated influenza vaccines from 2007–2017 When: Blood samples acquired before immunization (Day 0), on days 6–8 and 28 after immunization","2007–2013 Seasonal trivalent, inactivated influenza vaccines (Fluzone) 2014–2015 High Dose trivalent Fluzone for participants ≥ 65yo and quadrivalent Fluzone for younger participants",135 donors Assays: 51-plex Luminex 62-plex Luminex MSD 4plex MSD9plex Other Luminex HAI CMV/EBV Hormones CyTOF phenotype Lyoplate Phospho Cytof pheno Phospho cytof phospho Phosphoflow CBCD,SDY887 (2007) SDY212 (2008) SDY312 (2009) SDY311 (2010) SDY112 (2011) SDY315 (2012) SDY478 (2013) SDY1464 (2014),"8,9,– 10, 28, 37,38,39,40,41,42,43,44,45,– 46"
+1,SLVP017,NCT02133781 NCT03020498 NCT03020537,B-cell immunity to influenza (2009–2011 and 2013),"Who: 1–2yo (2013), 8–100yo healthy participants who did not receive the seasonal influenza vaccine in previous years (2010, 2011 and 2013) How: immunized with either seasonal inactivated or live, attenuated influenza vaccines in 2009, 2010, 2011 and 2013 When: Blood samples acquired before immunization (Day 0) and on day 28 after immunization","2009–2011 Seasonal trivalent, inactivated influenza vaccines (Fluzone) or seasonal live, attenuated influenza vaccine (FluMist) 2013 Seasonal trivalent inactivated influenza vaccine- (Fluzone) - pediatric formulation for 1–2yo children",153 donors Assays: 51-plex Luminex 62-plex Luminex HAI CMV/EBV CyTOF phenotype CBCD,SDY1467(2009) SDY1468(2010) SDY1469(2011) SDY1470(2012) SDY1471(2013),"27, 47,48,49,– 50"
+2,SLVP018,NCT01987349 NCT03022396 NCT03022422 NCT03022435 NCT03023176,T-cell and general immune response to seasonal influenza vaccine (2009–2013),"Who: 1–8yo (2013), 8–100yo healthy participants How: immunized with either seasonal inactivated or live, attenuated influenza vaccines from 2009–2013 When: Blood samples acquired before immunization (Day 0), days 7–10 and 28 after immunization","2009–2010 Seasonal trivalent inactivated influenza vaccine (Fluzone) or seasonal trivalent live attenuated influenza vaccine (FluMist) 2010 High Dose trivalent Fluzone for participants ≥ 65yo 2013 Seasonal trivalent, inactivated influenza Pediatric Dose (Fluzone, 0.25 ml) for 1–3yo children",249 donors Assays: 51-plex Luminex 62-plex Luminex MSD 4plex MSD 9plex HAI CMV/EBV Hormones CyTOF phenotype Lyoplate Phospho Cytof pheno Phospho cytof phospho Phosphoflow CBCD,SDY514(2009) SDY515(2010) SDY519(2011) SDY1465(2012) SDY1466(2013),"27, 44, 51,52,53,54,55,56,– 57"
+3,SLVP021,NCT02141581,Plasmablast trafficking and antibody response in influenza vaccination (2011–2014),"Who: 8–34yo healthy participants who did not receive the seasonal influenza vaccine in previous years How: immunized with either seasonal inactivated influenza vaccines, given intramuscularly or intradermally, or live, attenuated influenza vaccines from 2011–2014 When: Blood samples acquired before immunization (Day 0), days 6–8 and 24–32 after immunization",2011–2014 Seasonal trivalent inactivated influenza vaccine (Fluzone) given either intramuscularly or intradermally 2011–2012 Seasonal trivalent live attenuated influenza vaccine (FluMist),84 donors Assays: 51-plex Luminex 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype Phospho Cytof pheno Phospho cytof phospho Phosphoflow CBCD,SDY113 (2011) SDY305 (2012) SDY472 (2013) SDY1479 (2014),"58,59,– 60"
+4,SLVP024,NCT03023683,Protective mechanisms against a pandemic respiratory virus (2012),"Who: 2–49yo healthy participants How: immunized with the seasonal live, attenuated influenza vaccine When: Blood samples only from 18–42yo adults acquired before immunization (Day 0), days 7 and 28 after immunization","Seasonal live, attenuated influenza vaccine (FluMist)",Donors: 8 Assays: HAI Phosphoflow,SDY1472,Â
+5,SLVP028,NCT03088904,Genetic and environmental factors in the response to influenza vaccination (2014–2018),"Who: 12–49yo healthy participants How: immunized with either seasonal inactivated or live, attenuated influenza vaccines from 2014–2018 When: Blood samples acquired before immunization (Day 0), days 6–8 and 28 + 7 after immunization",Seasonal quadrivalent inactivated influenza vaccine (Fluzone) or seasonal quadrivalent live attenuated influenza vaccine (FluMist),Donors: 52 Assays: 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype,SDY1480 (2014) SDY1481 (2015),Â
+6,SLVP029,NCT03028974,Innate and acquired immunity to influenza infection and immunization (2014–2017),"Who: 6 mo-49yo healthy participants (who did not receive LAIV in the prior season nor received influenza immunizations in two or more prior seasons) How: immunized with either seasonal inactivated or live, attenuated influenza vaccines from 2014–2017 When: Blood samples acquired before immunization (Day 0), days 7 and 28 after immunization. Children <9 yrs received 2 immunizations with the second blood samples acquired 28 days after second immunization",Seasonal quadrivalent inactivated influenza vaccine (Fluzone) or seasonal quadrivalent live attenuated influenza vaccine (FluMist),Donors: 47 Assays: 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype,SDY1482 (2014) SDY1483 (2015),Â
+7,SLVP030,NCT03453801,"The role of CD4+ memory phenotype, memory, and effector t cells in vaccination and infection (2014–2019)","Who: 6 mo-10yo healthy participants How: immunized annually with either seasonal inactivated or live, attenuated influenza vaccines from 2014–2019 When: Blood samples acquired before immunization (Day 0), days 7 and 60 after immunization. Children with no prior influenza vaccine received 2 immunizations with the second blood sample acquired 60 days after second immunization","Seasonal quadrivalent inactivated influenza vaccine (Fluzone) or seasonal quadrivalent live attenuated influenza vaccine (FluMist) Seasonal trivalent, inactivated influenza Pediatric Dose (Fluzone, 0.25 ml) for 6–35mo children",Donors: 12 Assays: 62-plex Luminex HAI CMV/EBV Hormones CyTOF phenotype,SDY1484 (2014),Â